Wednesday, April 17, 2013

Making nylon in orgo lab

Below is a picture taken by a current student (Lynn) of the process of nylon-6,6 preparation from adipoyl chloride and hexamethylene diamine. The reaction proceeds in the presence of a base, to improve the nucleophilicity of the amine. The leaving group is the chloride ion.

The reaction resembles the synthesis of proteins in living systems, where tRNA acts as the leaving group after the amine of an amino acid performs the nucleophilic attack.

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